Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | APLNR | P35414 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3138241 | 0.78 | SIRT6 (0.56) | SIRT6APLNRTUBB4ATUBBTUBA3C | |
| SCHEMBL31039780 | 0.76 | NNMT (0.43) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3253381 | 0.76 | MAPK1 (0.45) | SIRT6LMNAGRM5 | |
| SCHEMBL17541069 | 0.74 | SIRT6 (0.42) | SIRT6APLNRLMNASMN1; SMN2TUBB4A | |
| SCHEMBL27556535 | 0.72 | NAAA (0.42) | SMN1; SMN2 | |
| SCHEMBL14279346 | 0.71 | SIRT6 (0.40) | SIRT6APLNRLMNASMN1; SMN2TUBB4A | |
| SCHEMBL31294478 | 0.71 | SIRT6 (0.43) | SIRT6APLNRLMNASMN1; SMN2TUBB4A | |
| SCHEMBL22374062 | 0.71 | APLNR (0.49) | SIRT6APLNRLMNASMN1; SMN2TUBB4A | |
| Water SCHEMBL27576541 | 0.71 | NAAA (0.41) | SMN1; SMN2 | |
| SCHEMBL18035007 | 0.71 | GRM5 (0.49) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107105667-B | Probes for imaging huntingtin | CHDI基金会股份有限公司 | 2021-08-17 | — | — | CN | disclosed |