SCHEMBL25869374 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	USP2	O75604	1/20	0.40

▸	SMN1; SMN2	Q16637	1/20	0.40

▸	NR1H2	P55055	1/20	0.38

▸	SCD5	Q86SK9	1/20	0.38

▸	RECQL	P46063	1/20	0.36

▸	DDB1	Q16531	1/20	0.36

▸	CRBN	Q96SW2	1/20	0.36

▸	RORC	P51449	2/20	0.36

▸	ACACB	O00763	4/20	0.35

▸	HPGD	P15428	1/20	0.35

▸	EPHX2	P34913	1/20	0.35

▸	CYP11B2	P19099	1/20	0.34

▸	GPR183	P32249	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25869375	0.83	RORC (0.39)	USP2SMN1; SMN2NR1H2SCD5RECQL
SCHEMBL29580095	0.82	NR1H2 (0.45)	USP2SMN1; SMN2NR1H2SCD5RECQL
SCHEMBL22720414	0.78	NR1H2 (0.41)	USP2SMN1; SMN2NR1H2SCD5RECQL
SCHEMBL22241106	0.77	USP2 (0.46)	USP2SMN1; SMN2RECQLHPGDEPHX2
SCHEMBL21851985	0.77	USP2 (0.46)	USP2SMN1; SMN2RECQLHPGDEPHX2
SCHEMBL21279710	0.77	USP2 (0.47)	USP2SMN1; SMN2NR1H2RECQLHPGD
SCHEMBL16573803	0.76	USP2 (0.48)	USP2SMN1; SMN2NR1H2SCD5RECQL
SCHEMBL23890773	0.74	USP2 (0.57)	USP2SMN1; SMN2NR1H2RECQLHPGD
SCHEMBL16664672	0.74	USP2 (0.57)	USP2SMN1; SMN2NR1H2RECQLHPGD
SCHEMBL1515253	0.74	USP2 (0.57)	USP2SMN1; SMN2NR1H2RECQLHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023134656-A1	PEPTIDYL NITRILE COMPOUND AND USE THEREOF	上海壹典医药科技开发有限公司	2023-07-20	—	—	WO	disclosed