SCHEMBL25869453

SCHEMBL25869453

C=C(C)C(=O)OCCCc1ccc(-c2ccc3c(sc4c(F)c(OC(=O)C(=C)C)ccc43)c2F)cc1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MPL P40238 8/20 0.32
TSHR P16473 2/20 0.32
RARB P10826 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25854858 0.94 MPL (0.32) POLBAPEX1HTTTDP1MPL
SCHEMBL25854938 0.93 MET (0.31) POLBAPEX1HTTTDP1
SCHEMBL25855183 0.93 MPL (0.34) POLBAPEX1HTTTDP1MPL
SCHEMBL25855605 0.92 MPL (0.32) POLBAPEX1HTTTDP1MPL
SCHEMBL25854946 0.92 NR1H2 (0.31) POLBAPEX1HTTTDP1
SCHEMBL25855037 0.91 FFAR4 (0.30)
SCHEMBL25855999 0.91 NR1H2 (0.33) POLBAPEX1HTTTDP1
SCHEMBL25854776 0.90 MPL (0.31) MPLRARB
SCHEMBL25856224 0.90 MPL (0.31) POLBAPEX1HTTTDP1MPL
SCHEMBL25860724 0.87 MCL1 (0.33) POLBAPEX1HTTTDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134598-A1 POLYMERISABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed