SCHEMBL25869561

SCHEMBL25869561

c1ccc(-c2cccc(N(c3ccc(-c4ccc5ccccc5c4)cc3)c3ccc(-c4cc5ccccc5c5c4oc4ccccc45)cc3)c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 3/20 0.35
RAB9A P51151 3/20 0.33
HSD17B1 P14061 2/20 0.33
HSD17B2 P37059 2/20 0.33
KDM4E B2RXH2 2/20 0.33
ANO1 Q5XXA6 1/20 0.33
CDC14B O60729 1/20 0.33
CDC14A Q9UNH5 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAOB P27338 1/20 0.33
CYP1A2 P05177 3/20 0.33
CYP1A1 P04798 2/20 0.33
PLA2G2A P14555 2/20 0.33
PLA2G4A P47712 2/20 0.33
FYN P06241 1/20 0.33
MAPK3 P27361 1/20 0.33
AHR P35869 1/20 0.33
PAX8 Q06710 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
PGR P06401 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25869758 0.98 GPR84 (0.34) GPR84RAB9AKDM4EANO1CDC14B
SCHEMBL25869341 0.96 GPR84 (0.36) GPR84RAB9AHSD17B1HSD17B2KDM4E
SCHEMBL25869565 0.96 GPR84 (0.36) GPR84RAB9AHSD17B1HSD17B2KDM4E
SCHEMBL25517698 0.96 GPR84 (0.38) GPR84RAB9AKDM4ECDC14BCDC14A
SCHEMBL19961052 0.94 GPR84 (0.38) GPR84RAB9AKDM4ECDC14BCDC14A
SCHEMBL24888164 0.93 GPR84 (0.34) GPR84RAB9AHSD17B1HSD17B2KDM4E
SCHEMBL24888407 0.93 GPR84 (0.34) GPR84RAB9AHSD17B1HSD17B2KDM4E
SCHEMBL25869201 0.92 GPR84 (0.34) GPR84RAB9AHSD17B1HSD17B2KDM4E
SCHEMBL25869356 0.92 PLA2G2A (0.39) GPR84RAB9AHSD17B1HSD17B2KDM4E
SCHEMBL25869442 0.91 CA12 (0.39) GPR84RAB9AKDM4ECDC14BCDC14A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023132694-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-07-13 WO disclosed