Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 9/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25870573 | 0.86 | PTPN1 (0.45) | EPHX2ALDH1A1ITGB3ITGA2BMEN1 | |
| SCHEMBL8375991 | 0.80 | KEAP1 (0.44) | EPHX1CHRM5CHRM3KMT2A | |
| SCHEMBL10199651 | 0.79 | KMT2A (0.45) | EPHX2EPHX1CHRM5CHRM3MEN1 | |
| SCHEMBL23842030 | 0.79 | EPHX2 (0.44) | EPHX2ALDH1A1EPHX1 | |
| SCHEMBL7839569 | 0.79 | CHRM5 (0.40) | ALDH1A1EPHX1CHRM5CHRM3KMT2A | |
| SCHEMBL24509167 | 0.78 | EPHX2 (0.50) | EPHX2EPHX1 | |
| SCHEMBL7882899 | 0.77 | KMT2A (0.53) | EPHX2EPHX1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19000030 | 0.77 | SLC6A4 (0.43) | EPHX2ALDH1A1EPHX1CHRM5CHRM3 | |
| SCHEMBL5889076 | 0.77 | YAP1 (0.56) | ALDH1A1EPHX1YAP1 | |
| SCHEMBL23866566 | 0.77 | DPP4 (0.42) | EPHX2ITGB3ITGA2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116920-A1 | PENTA- FUSED HEXA-HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | 杭州多域生物技术有限公司 | 2023-06-29 | — | — | WO | disclosed |