Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.34 |
| ▸ | MEN1 | O00255 | 6/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.33 |
| ▸ | CYBB | P04839 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 2/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18863393 | 0.90 | MAPT (0.40) | MAPTKMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL25870735 | 0.87 | LMNA (0.39) | MAPTKMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL25870688 | 0.87 | MAPT (0.36) | MAPTKMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL25870710 | 0.86 | MAPT (0.37) | MAPTKMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL25870713 | 0.83 | MEN1 (0.31) | MAPTKMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL18863386 | 0.82 | MAPT (0.39) | MAPTKMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL25870740 | 0.82 | MAPT (0.39) | MAPTKMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL25870678 | 0.81 | MAPT (0.40) | MAPTKMT2AMEN1SMN1; SMN2EP300 | |
| SCHEMBL18863387 | 0.81 | CISD1 (0.39) | MAPTKMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL25870691 | 0.81 | MAPT (0.35) | MAPTKMT2AMEN1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11711930-B2 | — | — | 2023-07-25 | — | — | US | disclosed |