SCHEMBL25870735

SCHEMBL25870735

CN1C(=O)C(=Cc2ccc(N(c3ccccc3)c3ccc(F)cc3)[se]2)C(=O)N(C)C1=S

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
MAPT P10636 7/20 0.36
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NOX4 Q9NPH5 5/20 0.35
CYBB P04839 4/20 0.35
HTT P42858 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
NOX1 Q9Y5S8 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
EP300 Q09472 1/20 0.34
ALDH1A1 P00352 3/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
NPC1 O15118 1/20 0.33
POLB P06746 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25870740 0.95 MAPT (0.39) LMNAMAPTMEN1KMT2ARAB9A
SCHEMBL18863393 0.94 MAPT (0.40) LMNAMAPTMEN1KMT2ARAB9A
SCHEMBL25870688 0.91 MAPT (0.36) MAPTMEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL25870710 0.90 MAPT (0.37) LMNAMAPTMEN1KMT2ARAB9A
SCHEMBL25870715 0.87 MAPT (0.34) MAPTMEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL18863386 0.85 MAPT (0.39) MAPTMEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL25870729 0.85 LMNA (0.34) LMNAMAPTMEN1KMT2ARAB9A
SCHEMBL25870726 0.85 LMNA (0.34) LMNAMAPTMEN1KMT2ARAB9A
SCHEMBL25870678 0.85 MAPT (0.40) LMNAMAPTMEN1KMT2ASMN1; SMN2
SCHEMBL18863387 0.84 CISD1 (0.39) LMNAMAPTMEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11711930-B2 2023-07-25 US disclosed