Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | USP5 | P45974 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035994 | 0.83 | NPSR1 (0.54) | HPGDNPSR1MCOLN3LMNAALDH1A1 | |
| SCHEMBL25870881 | 0.82 | USP5 (0.50) | HPGDCYP2C9USP5HTTLMNA | |
| SCHEMBL1827276 | 0.81 | HPGD (0.56) | HPGDNPSR1MCOLN3LMNAALDH1A1 | |
| SCHEMBL2921303 | 0.81 | HPGD (0.56) | HPGDNPSR1MCOLN3HTTLMNA | |
| SCHEMBL12988880 | 0.81 | NPSR1 (0.66) | HPGDNPSR1MCOLN3HTTLMNA | |
| SCHEMBL103818 | 0.81 | SMN1; SMN2 (0.55) | HPGDCYP2C9USP5HTTLMNA | |
| SCHEMBL1825385 | 0.79 | HPGD (0.54) | HPGDNPSR1MCOLN3LMNAALDH1A1 | |
| SCHEMBL2462624 | 0.79 | NPSR1 (0.54) | HPGDNPSR1MCOLN3LMNAALDH1A1 | |
| SCHEMBL4102311 | 0.79 | NPSR1 (0.60) | HPGDNPSR1MCOLN3LMNAALDH1A1 | |
| SCHEMBL2882577 | 0.79 | NPSR1 (0.54) | HPGDNPSR1MCOLN3LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174470-A1 | COMPOUND AS A UBR BOX DOMAIN LIGAND | AUTOTAC INC. (KR) | 2023-06-08 | — | — | US | disclosed |
| US-20230174470-A1 | COMPOUND AS A UBR BOX DOMAIN LIGAND | AUTOTAC INC. (KR) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174470-A1 | COMPOUND AS A UBR BOX DOMAIN LIGAND | UBR4, UBQLN2, UBTF | HPGD 4033/4885NPSR1 1238/4885MCOLN3 3339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.