SCHEMBL258713

SCHEMBL258713

CCCCCCCCCCCCCCCCCC(N)N(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.50
PLA2G1B P04054 1/20 0.48
PLA2G2A P14555 1/20 0.48
SPHK1 Q9NYA1 2/20 0.46
CYP2D6 P10635 2/20 0.43
LMNA P02545 2/20 0.43
TP53 P04637 2/20 0.43
LAP3 P28838 2/20 0.43
GMNN O75496 1/20 0.43
POLB P06746 1/20 0.43
THPO P40225 1/20 0.43
MTOR P42345 1/20 0.43
BLM P54132 1/20 0.43
KDM4E B2RXH2 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPT P10636 1/20 0.43
CETP P11597 1/20 0.43
HTT P42858 1/20 0.43
UBE2N P61088 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258375 1.00 OPRM1 (0.50) OPRM1PLA2G1BPLA2G2ASPHK1CYP2D6
SCHEMBL258476 1.00 OPRM1 (0.50) OPRM1PLA2G1BPLA2G2ASPHK1CYP2D6
SCHEMBL27904767 1.00 OPRM1 (0.50) OPRM1PLA2G1BPLA2G2ASPHK1CYP2D6
SCHEMBL464962 1.00 OPRM1 (0.50) OPRM1PLA2G1BPLA2G2ASPHK1CYP2D6
SCHEMBL3688932 1.00 OPRM1 (0.50) OPRM1PLA2G1BPLA2G2ASPHK1CYP2D6
SCHEMBL258727 1.00 OPRM1 (0.50) OPRM1PLA2G1BPLA2G2ASPHK1CYP2D6
SCHEMBL11030859 1.00 OPRM1 (0.50) OPRM1PLA2G1BPLA2G2ASPHK1CYP2D6
SCHEMBL18042663 1.00 OPRM1 (0.50) OPRM1PLA2G1BPLA2G2ASPHK1CYP2D6
SCHEMBL11862270 1.00 OPRM1 (0.50) OPRM1PLA2G1BPLA2G2ASPHK1CYP2D6
SCHEMBL421180 0.97 OPRM1 (0.52) OPRM1PLA2G1BPLA2G2ASPHK1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8063161-B2 Low temperature curing acrylate and maleimide based formulations and methods for use thereof DESIGNER MOLECULES, INC. (US) 2011-11-22 US claimed
US-20100063184-A1 LOW TEMPERATURE CURING ACRYLATE AND MALEIMIDE BASED FORMULATIONS AND METHODS FOR USE THEREOF DESIGNER MOLECULES, INC. (US) 2010-03-11 US claimed
WO-2008130894-A1 LOW TEMPERATURE CURING ACRYLATE AND MALEIMIDE BASED FORMULATIONS AND METHODS FOR USE THEREOF DESIGNER MOLECULES, INC. (US) 2008-10-30 WO claimed
US-6762172-B1 ANTIMICROBIAL SILANE CONTAINING A HYDROLYZABLE GROUP AND OPTIONALLY A NONHYDROLIZABLE ORGANIC GROUP, AN ORGANIC CARBONATE STABILIZER; NONHYDROLIZING SHELF STABLE SOLUTION NOVA BIOGENETICS, INC. 2004-07-13 US claimed
US-10961227-B2 Pigment dispersing agent, pigment composition, and pigment coloring agent DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2021-03-30 US disclosed
US-20200377480-A1 PIGMENT DISPERSING AGENT, PIGMENT COMPOSITION, AND PIGMENT COLORING AGENT DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2020-12-03 US disclosed
EP-3702413-A1 PIGMENT DISPERSING AGENT, PIGMENT COMPOSITION, AND PIGMENT COLORING AGENT Dainichiseika Color & Chemicals Mfg. Co., Ltd. (JP) 2020-09-02 EP disclosed
CN-107344914-B A kind of synthesis technology of antibacterial debonding agent, antibacterial debonding agent and purposes 陕西科技大学 2019-07-12 CN disclosed
US-8063161-B2 Low temperature curing acrylate and maleimide based formulations and methods for use thereof DESIGNER MOLECULES, INC. (US) 2011-11-22 US disclosed
US-20100063184-A1 LOW TEMPERATURE CURING ACRYLATE AND MALEIMIDE BASED FORMULATIONS AND METHODS FOR USE THEREOF DESIGNER MOLECULES, INC. (US) 2010-03-11 US disclosed
WO-2008130894-A1 LOW TEMPERATURE CURING ACRYLATE AND MALEIMIDE BASED FORMULATIONS AND METHODS FOR USE THEREOF DESIGNER MOLECULES, INC. (US) 2008-10-30 WO disclosed
CN-101121666-A Process for producing amino compound KOKURA SYNTHETIC IND LTD (JP) 2008-02-13 CN disclosed
US-5961711-A ANTHRAQUINONYLAMINOTRIAZINES DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 1999-10-05 US disclosed
EP-0848043-A2 Pigment dispersant and pigment dispersion, especially suitable for color filters DAINICHISEIKA COLOR & CHEMICALS MFG. CO. LTD. (JP) 1998-06-17 EP disclosed
US-3941808-A POLYAMIDE AMINE SALTS OF A STYRENE-MALEIC ANHYDRIDE COPOLYMER ATLANTIC RICHFIELD COMPANY (US) 1976-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10961227-B2 Pigment dispersing agent, pigment composition, and pigment coloring agent RB1, TYR, IK OPRM1 1775/4885PLA2G1B 2033/4885PLA2G2A 1664/4885
US-20200377480-A1 PIGMENT DISPERSING AGENT, PIGMENT COMPOSITION, AND PIGMENT COLORING AGENT TYR, PIM1, RB1 OPRM1 1522/4885PLA2G1B 3399/4885PLA2G2A 2927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.