SCHEMBL258727

SCHEMBL258727

CCCCCCCCCCCCCCCC(N)N(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.50
PLA2G1B P04054 1/20 0.48
PLA2G2A P14555 1/20 0.48
SPHK1 Q9NYA1 2/20 0.46
CYP2D6 P10635 2/20 0.43
LMNA P02545 2/20 0.43
TP53 P04637 2/20 0.43
LAP3 P28838 2/20 0.43
GMNN O75496 1/20 0.43
POLB P06746 1/20 0.43
THPO P40225 1/20 0.43
MTOR P42345 1/20 0.43
BLM P54132 1/20 0.43
KDM4E B2RXH2 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPT P10636 1/20 0.43
CETP P11597 1/20 0.43
HTT P42858 1/20 0.43
UBE2N P61088 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258375 1.00 OPRM1 (0.50) OPRM1PLA2G1BPLA2G2ASPHK1CYP2D6
SCHEMBL258476 1.00 OPRM1 (0.50) OPRM1PLA2G1BPLA2G2ASPHK1CYP2D6
SCHEMBL27904767 1.00 OPRM1 (0.50) OPRM1PLA2G1BPLA2G2ASPHK1CYP2D6
SCHEMBL464962 1.00 OPRM1 (0.50) OPRM1PLA2G1BPLA2G2ASPHK1CYP2D6
SCHEMBL3688932 1.00 OPRM1 (0.50) OPRM1PLA2G1BPLA2G2ASPHK1CYP2D6
SCHEMBL11030859 1.00 OPRM1 (0.50) OPRM1PLA2G1BPLA2G2ASPHK1CYP2D6
SCHEMBL18042663 1.00 OPRM1 (0.50) OPRM1PLA2G1BPLA2G2ASPHK1CYP2D6
SCHEMBL258713 1.00 OPRM1 (0.50) OPRM1PLA2G1BPLA2G2ASPHK1CYP2D6
SCHEMBL11862270 1.00 OPRM1 (0.50) OPRM1PLA2G1BPLA2G2ASPHK1CYP2D6
SCHEMBL421180 0.97 OPRM1 (0.52) OPRM1PLA2G1BPLA2G2ASPHK1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8063161-B2 Low temperature curing acrylate and maleimide based formulations and methods for use thereof DESIGNER MOLECULES, INC. (US) 2011-11-22 US claimed
US-20100063184-A1 LOW TEMPERATURE CURING ACRYLATE AND MALEIMIDE BASED FORMULATIONS AND METHODS FOR USE THEREOF DESIGNER MOLECULES, INC. (US) 2010-03-11 US claimed
WO-2008130894-A1 LOW TEMPERATURE CURING ACRYLATE AND MALEIMIDE BASED FORMULATIONS AND METHODS FOR USE THEREOF DESIGNER MOLECULES, INC. (US) 2008-10-30 WO claimed
EP-3362494-B1 POLYURETHANE CATALYSTS FROM SULFUR BASED SALTS EVONIK OPERATIONS GMBH (DE) 2023-08-16 EP disclosed
US-10570245-B2 Polyurethane catalysts from sulfur based salts EVONIK OPERATIONS GMBH (DE) 2020-02-25 US disclosed
US-20160229945-A1 POLYURETHANE CATALYSTS FROM SULFUR BASED SALTS AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-08-11 US disclosed
US-8063161-B2 Low temperature curing acrylate and maleimide based formulations and methods for use thereof DESIGNER MOLECULES, INC. (US) 2011-11-22 US disclosed
US-20100063184-A1 LOW TEMPERATURE CURING ACRYLATE AND MALEIMIDE BASED FORMULATIONS AND METHODS FOR USE THEREOF DESIGNER MOLECULES, INC. (US) 2010-03-11 US disclosed
WO-2008130894-A1 LOW TEMPERATURE CURING ACRYLATE AND MALEIMIDE BASED FORMULATIONS AND METHODS FOR USE THEREOF DESIGNER MOLECULES, INC. (US) 2008-10-30 WO disclosed