Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821000 | 0.85 | EGLN2 (0.35) | EGLN2ADRB2ADRB1ALDH1A1TSHR | |
| SCHEMBL25871526 | 0.81 | KHK (0.32) | KHK | |
| SCHEMBL25871524 | 0.79 | XDH (0.40) | ADRB2ADRB1KHK | |
| SCHEMBL23948129 | 0.78 | EGLN2 (0.37) | EGLN2ADRB2ADRB1ALDH1A1TSHR | |
| SCHEMBL22724579 | 0.77 | ALDH1A1 (0.40) | ALDH1A1TSHRTP53CYP3A4TDP1 | |
| SCHEMBL22063008 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TSHRTP53CYP3A4TDP1 | |
| SCHEMBL31433854 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TSHRTP53CYP3A4TDP1 | |
| Hydrochloric Acid SCHEMBL34461204 | 0.74 | ALDH1A1 (0.37) | ALDH1A1TSHRTP53CYP3A4TDP1 | |
| SCHEMBL21051816 | 0.72 | KDM4E (0.40) | EGLN2ALDH1A1TSHRCYP3A4KDM4E | |
| SCHEMBL2656947 | 0.72 | TSHR (0.36) | EGLN2ADRB2ALDH1A1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137634-A1 | TRICYCLIC COMPOUND, PREPARATION THEREFOR, PHARMACEUTICAL COMPOSITION AND USE | 上海奕拓医药科技有限责任公司 | 2023-07-27 | — | — | WO | disclosed |