SCHEMBL25871948

SCHEMBL25871948

CC(C)COC(=O)Cn1c(=O)oc2ccc(Br)cc21

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.60
▸ CBX7 O95931 4/20 0.52
▸ CDYL Q9Y232 4/20 0.52
▸ CDY1; CDY1B Q9Y6F8 4/20 0.52
▸ CDYL2 Q8N8U2 3/20 0.52
▸ SIGMAR1 Q99720 1/20 0.43
▸ TP53 P04637 1/20 0.43
▸ KMT2A Q03164 2/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ IDO1 P14902 1/20 0.42
▸ DRD1 P21728 1/20 0.41
▸ KMO O15229 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25307601 0.86 L3MBTL1 (0.58) L3MBTL1CBX7CDYLCDY1; CDY1BCDYL2
SCHEMBL20472305 0.81 CBX7 (0.54) L3MBTL1CBX7CDYLCDY1; CDY1BCDYL2
SCHEMBL30660243 0.81 CBX7 (0.54) L3MBTL1CBX7CDYLCDY1; CDY1BCDYL2
SCHEMBL16932296 0.79 CBX7 (0.60) L3MBTL1CBX7CDYLCDY1; CDY1BCDYL2
SCHEMBL30538038 0.79 CBX7 (0.60) L3MBTL1CBX7CDYLCDY1; CDY1BCDYL2
SCHEMBL22315069 0.79 L3MBTL1 (0.53) L3MBTL1
SCHEMBL5422054 0.78 CBX7 (0.54) L3MBTL1CBX7CDYLCDY1; CDY1BCDYL2
SCHEMBL30660242 0.78 CBX7 (0.62) CBX7CDYLCDY1; CDY1BCDYL2SIGMAR1
SCHEMBL5416540 0.78 CBX7 (0.62) CBX7CDYLCDY1; CDY1BCDYL2SIGMAR1
SCHEMBL22315055 0.78 L3MBTL1 (0.52) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219938-A1 COMPOUNDS AND THEIR METHODS OF USE PRAXIS PREC MEDICINES INC (US) 2023-07-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219938-A1 COMPOUNDS AND THEIR METHODS OF USE SCN1A, SCN3A, SCN1B L3MBTL1 1392/4885CBX7 1133/4885CDYL 2252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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