Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TSPO | P30536 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22315055 | 0.87 | L3MBTL1 (0.52) | L3MBTL1TSPO | |
| SCHEMBL20471932 | 0.85 | TSPO (0.48) | L3MBTL1TSPO | |
| SCHEMBL20472587 | 0.84 | TSPO (0.53) | TSPO | |
| SCHEMBL22314206 | 0.79 | CDYL2 (0.55) | TSPO | |
| SCHEMBL25871948 | 0.79 | L3MBTL1 (0.60) | L3MBTL1 | |
| SCHEMBL5413687 | 0.78 | TSPO (0.79) | TSPO | |
| SCHEMBL22315172 | 0.78 | KMO (0.47) | L3MBTL1TSPO | |
| SCHEMBL22315029 | 0.73 | L3MBTL1 (0.49) | L3MBTL1TSPO | |
| SCHEMBL25864996 | 0.72 | TSPO (0.68) | TSPO | |
| SCHEMBL25865302 | 0.71 | TSPO (0.49) | TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219938-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PREC MEDICINES INC (US) | 2023-07-13 | — | — | US | disclosed |
| US-20200247793-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. (US) | 2020-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200247793-A1 | COMPOUNDS AND THEIR METHODS OF USE | SCN1A, SCN3A, SCN1B | L3MBTL1 1392/4885TSPO 394/4885 |
| US-20230219938-A1 | COMPOUNDS AND THEIR METHODS OF USE | SCN1A, SCN3A, SCN1B | L3MBTL1 1392/4885TSPO 394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.