Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12707417 | 0.85 | MEN1 (0.57) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL18773854 | 0.84 | SMN1; SMN2 (0.53) | ALDH1A1KDM4EHPGDLMNAMEN1 | |
| SCHEMBL21620313 | 0.81 | MEN1 (0.78) | ALDH1A1KDM4EHPGDLMNAMEN1 | |
| SCHEMBL18773874 | 0.75 | HSD17B10 (0.58) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL8071365 | 0.75 | NPC1 (0.56) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL24933726 | 0.74 | TDP1 (0.54) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL5931175 | 0.74 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDLMNAMEN1 | |
| SCHEMBL18499179 | 0.73 | HSD17B10 (0.66) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL18774009 | 0.73 | KCNK3 (0.51) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL24629001 | 0.73 | MEN1 (0.39) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3395795-B1 | MALONONITRILE OXIME ETHER COMPOUND AND USE THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2023-07-19 | — | — | EP | disclosed |