SCHEMBL25873163

SCHEMBL25873163

CC(C)(c1ccc(-c2ccc(N=C=O)cc2)cc1)c1ccc(-c2ccc(OC#N)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.34
TSHR P16473 1/20 0.34
KIF11 P52732 2/20 0.33
PTPN5 P54829 1/20 0.31
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25873160 1.00 CYP3A4 (0.34) CYP3A4TSHRKIF11PTPN5TRPA1
SCHEMBL12908787 0.96 TSHR (0.37) CYP3A4TSHRTRPA1
SCHEMBL10033172 0.88 CYP3A4 (0.42) CYP3A4TSHRTRPA1
SCHEMBL13084777 0.88 ESR1 (0.40) CYP3A4TSHRTRPA1
SCHEMBL25873141 0.87 CYP3A4 (0.37) CYP3A4TSHRTRPA1
SCHEMBL12581492 0.85 ALDH1A1 (0.34) CYP3A4TSHR
SCHEMBL22966364 0.84 KIF11 (0.42) CYP3A4TSHRKIF11PTPN5
SCHEMBL22966365 0.84 CYP3A4 (0.45) CYP3A4TSHRKIF11TRPA1
SCHEMBL22966431 0.84 KIF11 (0.42) CYP3A4TSHRKIF11PTPN5
SCHEMBL22966434 0.84 CYP3A4 (0.45) CYP3A4TSHRKIF11TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240016699-A1 PHARMACEUTICAL PACKAGES WITH COATINGS COMPRISING POLYCYANURATES CORNING INC (US) 2024-01-18 US disclosed
US-11707411-B2 Pharmaceutical packages with coatings comprising polycyanurates CORNING INCORPORATED (US) 2023-07-25 US disclosed