SCHEMBL25873179

SCHEMBL25873179

CC(C)(C)OC(=O)N[C@H]1CCC[C@H]2CC[C@@H](C(=O)OCc3ccccc3)N2C1=O

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 2/20 0.56
FKBP1A P62942 3/20 0.51
KMT2A Q03164 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
XIAP P98170 9/20 0.50
ACE P12821 1/20 0.47
BIRC3 Q13489 1/20 0.45
BIRC2 Q13490 1/20 0.45
CTSL P07711 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9973474 0.98 CASP1 (0.54) CASP1FKBP1AKMT2AL3MBTL1XIAP
SCHEMBL9973468 0.89 CASP1 (0.48) CASP1FKBP1AKMT2AL3MBTL1XIAP
SCHEMBL31384849 0.89 CASP1 (0.48) CASP1FKBP1AKMT2AL3MBTL1XIAP
SCHEMBL9973466 0.89 CASP1 (0.48) CASP1FKBP1AKMT2AL3MBTL1XIAP
SCHEMBL9973467 0.88 CASP1 (0.49) CASP1FKBP1AKMT2AL3MBTL1XIAP
SCHEMBL31384817 0.88 CASP1 (0.49) CASP1FKBP1AKMT2AL3MBTL1XIAP
SCHEMBL9973469 0.88 CASP1 (0.49) CASP1FKBP1AKMT2AL3MBTL1XIAP
SCHEMBL1299624 0.88 CASP1 (0.47) CASP1FKBP1AKMT2AL3MBTL1XIAP
SCHEMBL1299626 0.88 CASP1 (0.47) CASP1FKBP1AKMT2AL3MBTL1XIAP
SCHEMBL1299623 0.88 CASP1 (0.47) CASP1FKBP1AKMT2AL3MBTL1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215029-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 US disclosed
EP-4463459-A1 STAT MODULATORS AND USES THEREOF Recludix Pharma, Inc. (US) 2024-11-20 EP disclosed
CN-118804917-A STAT modulators and uses thereof 瑞克鲁迪克斯制药股份有限公司 2024-10-18 CN disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 WO disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215029-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A CASP1 2275/4885FKBP1A 1107/4885KMT2A 873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.