Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3879495 | 0.85 | ACACB (0.54) | HDAC6HDAC8PTGER1HRH3ACACB | |
| SCHEMBL20173793 | 0.83 | ALDH1A1 (0.51) | HDAC6HDAC8PTGER1HRH3ALDH1A1 | |
| SCHEMBL20173805 | 0.82 | HDAC6 (0.44) | HDAC6HDAC8PTGER1ALDH1A1HSP90AA1 | |
| SCHEMBL13791770 | 0.82 | HDAC6 (0.42) | HDAC6HDAC8PTGER1HRH3HDAC3 | |
| SCHEMBL26167813 | 0.82 | PTGER1 (0.44) | HDAC6HDAC8PTGER1HRH3HDAC3 | |
| SCHEMBL26161462 | 0.82 | HSD17B3 (0.51) | POLBHDAC6HDAC8PTGER1HRH3 | |
| Hydrochloric Acid SCHEMBL3880242 | 0.81 | PTGER1 (0.43) | HDAC6HDAC8PTGER1HRH3HDAC3 | |
| SCHEMBL20173800 | 0.80 | HDAC6 (0.46) | HDAC6HDAC8PTGER1HDAC3HDAC1 | |
| SCHEMBL21882599 | 0.80 | HDAC6 (0.43) | POLBHDAC6HDAC8PTGER1HSP90AA1 | |
| SCHEMBL4520343 | 0.80 | HRH3 (0.55) | HRH3ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227826-A1 | UNA OLIGOMERS FOR THE TREATMENT OF POLYGLUTAMINE DISEASES | ARCTURUS THERAPEUTICS, INC. | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227826-A1 | UNA OLIGOMERS FOR THE TREATMENT OF POLYGLUTAMINE DISEASES | HNRNPR, HNRNPK, ATXN2 | POLB 1561/4885HDAC6 1182/4885HDAC8 923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.