Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.60 |
| ▸ | APP | P05067 | 2/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.56 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | FABP2 | P12104 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24177869 | 0.90 | CYP2C19 (0.61) | MAOBLMNAMAPTSMN1; SMN2CYP2C19 | |
| SCHEMBL8755011 | 0.87 | LMNA (0.74) | MAOBLMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL13448835 | 0.87 | LMNA (0.74) | MAOBLMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL4217335 | 0.87 | LMNA (0.74) | MAOBLMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL8755392 | 0.87 | LMNA (0.74) | MAOBLMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL8755498 | 0.87 | LMNA (0.74) | MAOBLMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL1543120 | 0.87 | LMNA (0.74) | MAOBLMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL1543413 | 0.87 | LMNA (0.74) | MAOBLMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL8193598 | 0.86 | CYP2C19 (0.57) | MAOBLMNAMAPTCYP2C19APP | |
| Hydrochloric Acid SCHEMBL27850094 | 0.86 | LMNA (0.72) | MAOBLMNAMAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227425-A1 | REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227425-A1 | REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION | CFH, DOHH, CTSH | MAOB 151/4885LMNA 1741/4885MAPT 3465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.