SCHEMBL25873605

SCHEMBL25873605

CC(C)c1cc(Oc2c(Cl)cc(NC(C)c3noc(=O)[nH]3)cc2Cl)n[nH]c1=O

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 20/20 0.70
THRA P10827 17/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21749431 0.82 THRB (1.00) THRBTHRA
SCHEMBL21749453 0.82 THRB (1.00) THRBTHRA
SCHEMBL21769749 0.82 THRB (1.00) THRBTHRA
SCHEMBL21749520 0.82 THRB (1.00) THRBTHRA
SCHEMBL21749469 0.81 THRB (1.00) THRBTHRA
SCHEMBL22743621 0.81 THRB (0.79) THRBTHRA
SCHEMBL24032552 0.78 THRB (0.70) THRBTHRA
SCHEMBL22535224 0.77 THRB (0.72) THRBTHRA
SCHEMBL22660302 0.76 THRB (0.77) THRBTHRA
SCHEMBL16922218 0.76 THRB (0.66) THRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226038-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIVER DISORDERS VIKING THERAPEUTICS, INC. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226038-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIVER DISORDERS FABP1, SLC10A1, LIPC THRB 19/4885THRA 25/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.