Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.39 |
| ▸ | LPL | P06858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19608835 | 0.84 | LMNA (0.43) | FFAR4LMNASMN1; SMN2KMT2AMAPT | |
| SCHEMBL18914323 | 0.83 | MAPT (0.57) | FFAR4LMNASMN1; SMN2KMT2AMAPT | |
| SCHEMBL29417758 | 0.81 | SMN1; SMN2 (0.50) | LMNASMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL15101008 | 0.81 | SMN1; SMN2 (0.50) | LMNASMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL18701232 | 0.81 | NOTUM (0.54) | FFAR4LMNASMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL19582507 | 0.79 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL20794008 | 0.79 | LMNA (0.45) | FFAR4LMNASMN1; SMN2KMT2AMAPT | |
| SCHEMBL20566963 | 0.79 | HRH3 (0.56) | FFAR4LMNASMN1; SMN2ALDH1A1HRH3 | |
| SCHEMBL28615760 | 0.79 | GRM2 (0.45) | FFAR4LMNASMN1; SMN2KMT2AMAPT | |
| SCHEMBL18064748 | 0.78 | PIM1 (0.42) | LMNASMN1; SMN2KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3578545-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE PYRROLIDINE COMPOUNDS | MITSUBISHI TANABE PHARMA CORP (JP) | 2023-07-26 | — | — | EP | disclosed |