Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 3/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.37 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP4 | P49662 | 1/20 | 0.36 |
| ▸ | CASP5 | P51878 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29417758 | 0.83 | SMN1; SMN2 (0.50) | LMNASMN1; SMN2MGLLABHD6CYP2D6 | |
| SCHEMBL15101008 | 0.83 | SMN1; SMN2 (0.50) | LMNASMN1; SMN2MGLLABHD6CYP2D6 | |
| SCHEMBL5738243 | 0.82 | LMNA (0.50) | LMNASMN1; SMN2HTR1ACYP2D6KMT2A | |
| SCHEMBL19582507 | 0.81 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2MGLLABHD6CYP2D6 | |
| SCHEMBL25874298 | 0.79 | FFAR4 (0.45) | LMNASMN1; SMN2CYP2D6FFAR4KMT2A | |
| SCHEMBL15093911 | 0.79 | LMNA (0.66) | LMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29417642 | 0.79 | LMNA (0.47) | LMNASMN1; SMN2FFAR4KMT2AKDM4E | |
| SCHEMBL20503423 | 0.79 | ADRB2 (0.54) | LMNASMN1; SMN2HTR1AKMT2AALDH1A1 | |
| SCHEMBL18914793 | 0.79 | LMNA (0.47) | LMNASMN1; SMN2FFAR4KMT2AKDM4E | |
| SCHEMBL20769627 | 0.78 | ENPP2 (0.44) | LMNASMN1; SMN2MGLLABHD6CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019046330-A1 | SPIROCYCLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABIDE THERAPEUTICS, INC. (US) | 2019-03-07 | — | — | WO | disclosed |