Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 19/20 | 0.52 |
| ▸ | FLT3 | P36888 | 13/20 | 0.52 |
| ▸ | KIT | P10721 | 10/20 | 0.52 |
| ▸ | CSF1R | P07333 | 9/20 | 0.52 |
| ▸ | FLT4 | P35916 | 8/20 | 0.52 |
| ▸ | FLT1 | P17948 | 8/20 | 0.52 |
| ▸ | LYN | P07948 | 6/20 | 0.52 |
| ▸ | SRC | P12931 | 5/20 | 0.52 |
| ▸ | BLK | P51451 | 5/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.52 |
| ▸ | AURKA | O14965 | 4/20 | 0.52 |
| ▸ | PLK4 | O00444 | 3/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.52 |
| ▸ | CDK1 | P06493 | 3/20 | 0.52 |
| ▸ | MET | P08581 | 3/20 | 0.52 |
| ▸ | PRKACA | P17612 | 3/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.52 |
| ▸ | STK3 | Q13188 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25874379 | 0.92 | KDR (0.46) | KDRFLT3KITCSF1RFLT4 | |
| SCHEMBL25875120 | 0.91 | KDR (0.53) | KDRFLT3KITCSF1RFLT4 | |
| SCHEMBL25874330 | 0.87 | KDR (0.59) | KDRFLT3KITCSF1RFLT4 | |
| SCHEMBL25874336 | 0.87 | KDR (0.59) | KDRFLT3KITCSF1RFLT4 | |
| SCHEMBL25874689 | 0.86 | KDR (0.57) | KDRFLT3KITCSF1RFLT4 | |
| SCHEMBL21387231 | 0.84 | KDR (0.59) | KDRFLT3KITCSF1RFLT4 | |
| SCHEMBL25874656 | 0.84 | KDR (0.68) | KDRFLT3KITCSF1RFLT4 | |
| SCHEMBL21668692 | 0.83 | KDR (0.54) | KDRFLT3KITCSF1RFLT4 | |
| SCHEMBL25874744 | 0.83 | KDR (0.57) | KDRFLT3KITCSF1RFLT4 | |
| SCHEMBL21668628 | 0.82 | KDR (0.50) | KDRFLT3KITCSF1RFLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11712434-B2 | Compound having anti-cancer effect, and preparation method therefor and use thereof | 3D MEDICINES (BEIJING) CO., LTD. (CN) | 2023-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11712434-B2 | Compound having anti-cancer effect, and preparation method therefor and use thereof | HDGF, HGF, CYP4F11 | KDR 189/4885FLT3 157/4885KIT 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.