SCHEMBL25874358

SCHEMBL25874358

N#Cc1cccc(-c2ccccc2-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc(-c5nc6ccccc6o5)c4)c3)n2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 8/20 0.47
MEN1 O00255 7/20 0.47
KMT2A Q03164 7/20 0.47
CYP3A4 P08684 7/20 0.47
LMNA P02545 5/20 0.47
CYP2D6 P10635 5/20 0.47
ALDH1A1 P00352 4/20 0.47
CLK4 Q9HAZ1 4/20 0.47
HSD17B10 Q99714 4/20 0.47
CYP2C19 P33261 3/20 0.47
TSHR P16473 3/20 0.47
CYP2C9 P11712 2/20 0.47
TP53 P04637 3/20 0.44
MAPK1 P28482 3/20 0.44
KDM4E B2RXH2 1/20 0.43
MAPT P10636 1/20 0.43
GPR119 Q8TDV5 1/20 0.43
MGLL Q99685 1/20 0.43
HPSE Q9Y251 2/20 0.42
GRM5 P41594 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25874599 0.99 MEN1 (0.45) CYP1A2MEN1KMT2ACYP3A4LMNA
SCHEMBL26267814 0.94 HPSE (0.43) CYP1A2MEN1KMT2ACYP3A4LMNA
SCHEMBL25875041 0.93 TP53 (0.43) CYP1A2MEN1KMT2ACYP3A4LMNA
SCHEMBL26269457 0.92 CYP1A2 (0.51) CYP1A2MEN1KMT2ACYP3A4LMNA
SCHEMBL25874500 0.92 MEN1 (0.45) CYP1A2MEN1KMT2ACYP3A4LMNA
SCHEMBL25874444 0.91 PTGS2 (0.46) CYP1A2MEN1KMT2ACYP3A4LMNA
SCHEMBL25875023 0.90 TP53 (0.43) CYP1A2MEN1KMT2ACYP3A4LMNA
SCHEMBL25875202 0.86 PTGS2 (0.47) CYP1A2MEN1KMT2ACYP3A4LMNA
SCHEMBL27453707 0.85 CYP1A2 (0.53) CYP1A2MEN1KMT2ACYP3A4LMNA
SCHEMBL27453370 0.85 CYP1A2 (0.53) CYP1A2MEN1KMT2ACYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023140649-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-07-27 WO disclosed