SCHEMBL25874644

SCHEMBL25874644

Cc1ccc([Si](c2ccccc2)(c2ccccc2)c2cccc(-c3cc(-n4c5ccccc5c5ccccc54)cc(-n4c5ccccc5c5ccccc54)c3)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
ATM Q13315 1/20 0.39
LMNA P02545 3/20 0.35
HTT P42858 2/20 0.35
MAPT P10636 2/20 0.35
AKR1C4 P17516 1/20 0.34
AKR1C3 P42330 1/20 0.34
AKR1C2 P52895 1/20 0.34
AKR1C1 Q04828 1/20 0.34
ALDH1A1 P00352 5/20 0.34
GAA P10253 1/20 0.34
RXFP1 Q9HBX9 2/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 2/20 0.32
PPARG P37231 2/20 0.32
NCOA2 Q15596 2/20 0.32
NCOA1 Q15788 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25874642 0.92 L3MBTL1 (0.39) KDM4EL3MBTL1ATMMAPTALDH1A1
SCHEMBL26304998 0.92 L3MBTL1 (0.46) KDM4EL3MBTL1ATMHTTMAPT
SCHEMBL26426633 0.91 ATM (0.44) KDM4EL3MBTL1ATMHTTMAPT
SCHEMBL26214620 0.86 ALDH1A1 (0.34) KDM4EL3MBTL1ATMLMNAHTT
SCHEMBL26519446 0.85 L3MBTL1 (0.49) KDM4EL3MBTL1ATMLMNAHTT
SCHEMBL10090556 0.85 L3MBTL1 (0.41) KDM4EL3MBTL1ATMLMNAMAPT
SCHEMBL10090555 0.85 L3MBTL1 (0.41) KDM4EL3MBTL1ATMLMNAMAPT
SCHEMBL21688188 0.85 L3MBTL1 (0.52) KDM4EL3MBTL1ATMHTTMAPT
SCHEMBL12000710 0.85 L3MBTL1 (0.52) KDM4EL3MBTL1ATMHTTMAPT
SCHEMBL13864698 0.84 KDM4E (0.46) KDM4EL3MBTL1ATMLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363254-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 US disclosed
US-11716899-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-01 US disclosed