SCHEMBL25874709

SCHEMBL25874709

N#Cc1ccccc1-c1cccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4ccccc4-c4ccccc4-c4cccc(-c5nc6ccccc6o5)c4)c3)n2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 4/20 0.46
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
NPC1 O15118 4/20 0.42
PTGS2 P35354 2/20 0.41
RAB9A P51151 2/20 0.41
ATM Q13315 1/20 0.41
HPSE Q9Y251 1/20 0.41
KDM4E B2RXH2 7/20 0.41
ALDH1A1 P00352 5/20 0.41
HPGD P15428 4/20 0.41
HSD17B10 Q99714 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
PKM P14618 1/20 0.41
USP30 Q70CQ3 1/20 0.40
DUSP1 P28562 1/20 0.40
HCRTR1 O43613 1/20 0.40
NFKB1 P19838 1/20 0.40
STAT1 P42224 1/20 0.40
NFKB2 Q00653 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26268257 0.93 TP53 (0.46) TP53MEN1KMT2ANPC1RAB9A
SCHEMBL26268244 0.93 TP53 (0.42) TP53MEN1KMT2ANPC1PTGS2
SCHEMBL25864463 0.85 TP53 (0.44) TP53MEN1KMT2ANPC1RAB9A
SCHEMBL25874358 0.85 CYP1A2 (0.47) TP53MEN1KMT2ANPC1PTGS2
SCHEMBL25875041 0.84 TP53 (0.43) TP53MEN1KMT2ANPC1PTGS2
SCHEMBL25874599 0.83 MEN1 (0.45) TP53MEN1KMT2ANPC1PTGS2
SCHEMBL24353070 0.83 NPC1 (0.57) TP53MEN1KMT2ANPC1RAB9A
SCHEMBL27049311 0.82 NPC1 (0.55) TP53MEN1KMT2ANPC1RAB9A
SCHEMBL27453371 0.80 GABRG2 (0.48) MEN1KMT2AALDH1A1HPGDHSD17B10
SCHEMBL27453715 0.80 GABRG2 (0.48) MEN1KMT2AALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023140649-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-07-27 WO disclosed