Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 10/20 | 0.64 |
| ▸ | HTR2C | P28335 | 7/20 | 0.64 |
| ▸ | HTR2B | P41595 | 6/20 | 0.64 |
| ▸ | HTR1A | P08908 | 2/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.59 |
| ▸ | HTR1D | P28221 | 1/20 | 0.59 |
| ▸ | HTR1B | P28222 | 1/20 | 0.59 |
| ▸ | HTR1E | P28566 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.59 |
| ▸ | HTR7 | P34969 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | HTR5A | P47898 | 1/20 | 0.59 |
| ▸ | HTR6 | P50406 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10344616 | 0.83 | GPR84 (0.58) | HTR2AHTR2CHTR2BHTR1ADRD1 | |
| SCHEMBL26965700 | 0.82 | HTR2A (0.71) | HTR2AHTR2CHTR2BHTR1ADRD1 | |
| SCHEMBL15323836 | 0.81 | GAA (0.72) | HTR2AHTR2CHTR2BHTR1ADRD1 | |
| SCHEMBL26965635 | 0.79 | HTR2A (0.83) | HTR2AHTR2CHTR2BHTR1ADRD1 | |
| SCHEMBL21333752 | 0.79 | HTR2A (0.72) | HTR2AHTR2CHTR2BHTR1ADRD1 | |
| SCHEMBL6619709 | 0.79 | HTR2A (0.63) | HTR2AHTR2CHTR2BHTR1ADRD1 | |
| SCHEMBL27134372 | 0.79 | HTR2A (0.71) | HTR2AHTR2CHTR2BHTR1ADRD1 | |
| SCHEMBL31742960 | 0.78 | HTR2A (0.66) | HTR2AHTR2CHTR2BHTR1ADRD1 | |
| SCHEMBL30681613 | 0.78 | HTR2A (1.00) | HTR2AHTR2CHTR2BHTR1ADRD1 | |
| SCHEMBL8913458 | 0.78 | HTR2A (0.68) | HTR2AHTR2CHTR2BHTR1ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130076-A2 | TARGETS AND PATHWAYS FOR THE PRODUCTION OF ALKALOIDAL COMPOUNDS | Empyrean Neuroscience, Inc. (US) | 2023-07-06 | — | — | WO | disclosed |