SCHEMBL25875124

SCHEMBL25875124

CCC(CC(C)C(=O)NCCOCCOCCN)C(=O)N(C)C

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
USP2 O75604 1/20 0.38
TSHR P16473 1/20 0.38
TLR2 O60603 2/20 0.35
KIF11 P52732 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25875095 0.88 MEN1 (0.43) MEN1KMT2AUSP2TSHRCA2
SCHEMBL16941021 0.81 MEN1 (0.46) MEN1KMT2AUSP2TSHRTLR2
SCHEMBL13663154 0.74 MEN1 (0.45) MEN1KMT2AUSP2TSHRTLR2
SCHEMBL16941024 0.74 USP2 (0.46) MEN1KMT2AUSP2TSHRCA2
SCHEMBL23295081 0.73 KMT2A (0.61) MEN1KMT2AUSP2TSHRTLR2
SCHEMBL17175238 0.73 KMT2A (0.61) MEN1KMT2AUSP2TSHRTLR2
SCHEMBL22823027 0.73 KMT2A (0.61) MEN1KMT2AUSP2TSHRTLR2
SCHEMBL17853874 0.73 KMT2A (0.66) MEN1KMT2AUSP2TSHRTLR2
SCHEMBL12706032 0.72 MEN1 (0.49) MEN1KMT2ATLR2
SCHEMBL13255060 0.72 MEN1 (0.59) MEN1KMT2ATLR2KIF11CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212209-A1 COMPOSITIONS AND METHODS FOR LIQUID PHASE OLIGONUCLEOTIDE SYNTHESIS HONGENE BIOTECH CORPORATION 2023-07-06 US disclosed
US-20230212209-A1 COMPOSITIONS AND METHODS FOR LIQUID PHASE OLIGONUCLEOTIDE SYNTHESIS HONGENE BIOTECH CORPORATION 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212209-A1 COMPOSITIONS AND METHODS FOR LIQUID PHASE OLIGONUCLEOTIDE SYNTHESIS POLR2H, POLR2E, POLI MEN1 2649/4885KMT2A 2962/4885USP2 2354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.