Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16941021 | 0.92 | MEN1 (0.46) | USP2TSHRMEN1KMT2APOLB | |
| SCHEMBL16941025 | 0.81 | MEN1 (0.43) | USP2TSHRMEN1KMT2ACA1 | |
| SCHEMBL17358795 | 0.80 | USP2 (0.55) | USP2TSHRCA1CA2CA7 | |
| SCHEMBL9965936 | 0.80 | USP2 (0.48) | USP2TSHRMEN1KMT2APOLB | |
| SCHEMBL21401134 | 0.79 | MEN1 (0.44) | USP2TSHRMEN1KMT2APOLB | |
| SCHEMBL11810200 | 0.78 | TSHR (0.74) | USP2TSHRKMT2ACA1CA2 | |
| SCHEMBL16941026 | 0.76 | TSHR (0.38) | USP2TSHRMEN1KMT2APOLB | |
| SCHEMBL19841540 | 0.75 | DDAH1 (0.46) | MEN1KMT2APOLBHPGDDDAH1 | |
| SCHEMBL16941017 | 0.74 | MEN1 (0.40) | USP2TSHRMEN1KMT2ACA1 | |
| SCHEMBL25875124 | 0.74 | MEN1 (0.43) | USP2TSHRMEN1KMT2ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9795689-B2 | Crosslinked polymer nano-assemblies and uses thereof | UNIVERSITY OF MASSACHUSETTS (US) | 2017-10-24 | — | — | US | disclosed |
| US-20150209447-A1 | CROSSLINKED POLYMER NANO-ASSEMBLIES AND USES THEREOF | UNIVERSITY OF MASSACHUSETTS (US) | 2015-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150209447-A1 | CROSSLINKED POLYMER NANO-ASSEMBLIES AND USES THEREOF | MSN, PARG, PARN | USP2 242/4885TSHR 4491/4885MEN1 1955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.