Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23729793 | 0.92 | LMNA (0.46) | LMNASMN1; SMN2HPGDALDH1A1CYP2D6 | |
| SCHEMBL25516107 | 0.84 | LMNA (0.43) | LMNASMN1; SMN2HPGDALDH1A1CYP2D6 | |
| SCHEMBL25524815 | 0.84 | LMNA (0.43) | LMNASMN1; SMN2HPGDALDH1A1CYP2D6 | |
| SCHEMBL26147450 | 0.84 | LMNA (0.43) | LMNASMN1; SMN2HPGDALDH1A1CYP2D6 | |
| SCHEMBL26445199 | 0.84 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2HPGDALDH1A1CYP2D6 | |
| SCHEMBL26445198 | 0.84 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2HPGDALDH1A1CYP2D6 | |
| SCHEMBL20100737 | 0.83 | LMNA (0.45) | LMNASMN1; SMN2HPGDALDH1A1CYP2D6 | |
| SCHEMBL25831024 | 0.83 | KMT2A (0.46) | LMNASMN1; SMN2HPGDALDH1A1CYP2D6 | |
| SCHEMBL23560301 | 0.83 | KMT2A (0.46) | LMNASMN1; SMN2HPGDALDH1A1CYP2D6 | |
| SCHEMBL26700453 | 0.82 | LMNA (0.42) | LMNASMN1; SMN2HPGDALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116920-A1 | PENTA- FUSED HEXA-HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | 杭州多域生物技术有限公司 | 2023-06-29 | — | — | WO | disclosed |