SCHEMBL25875451

SCHEMBL25875451

C=CC(=O)Oc1ccc(-c2ccc3c(oc4c(F)c(OC(=O)C=C)ccc43)c2OC(F)(F)F)cc1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.33
LCK P06239 1/20 0.33
FYN P06241 1/20 0.33
CSF1R P07333 1/20 0.33
LYN P07948 1/20 0.33
KIT P10721 1/20 0.33
SRC P12931 1/20 0.33
FLT1 P17948 1/20 0.33
FLT4 P35916 1/20 0.33
KDR P35968 1/20 0.33
FLT3 P36888 1/20 0.33
BLK P51451 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
TYMS P04818 1/20 0.32
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25876847 0.93 ADORA3 (0.36) ABL1LCKFYNCSF1RLYN
SCHEMBL25876640 0.92 ADORA3 (0.35) ABL1LCKFYNCSF1RLYN
SCHEMBL25876567 0.89 ABL1 (0.33) ABL1LCKFYNCSF1RLYN
SCHEMBL25875785 0.89 KMT2A (0.36) ABL1LCKFYNCSF1RLYN
SCHEMBL25870131 0.89 ABL1 (0.38) ABL1LCKFYNCSF1RLYN
SCHEMBL25875376 0.88 ADORA3 (0.36) ADORA3TYMSTHRB
SCHEMBL25874031 0.87 TYMS (0.34) TYMSTHRB
SCHEMBL25876711 0.87 ABL1 (0.38) ABL1LCKFYNCSF1RLYN
SCHEMBL25875380 0.85 TYMS (0.33) ADORA3TYMSTHRB
SCHEMBL25875452 0.85 ADORA3 (0.34) ABL1LCKFYNCSF1RLYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134595-A1 POLYMERIZABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134594-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed