SCHEMBL25875785

SCHEMBL25875785

C=CC(=O)Oc1ccc(-c2ccc3c(oc4c(C)c(OC(=O)C=C)ccc43)c2OC(F)(F)F)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.36
GAA P10253 2/20 0.36
HTT P42858 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
MEN1 O00255 2/20 0.35
ABL1 P00519 1/20 0.34
LCK P06239 1/20 0.34
FYN P06241 1/20 0.34
CSF1R P07333 1/20 0.34
LYN P07948 1/20 0.34
KIT P10721 1/20 0.34
SRC P12931 1/20 0.34
FLT1 P17948 1/20 0.34
FLT4 P35916 1/20 0.34
KDR P35968 1/20 0.34
FLT3 P36888 1/20 0.34
BLK P51451 1/20 0.34
ESR1 P03372 1/20 0.33
THRB P10828 2/20 0.32
TEAD1 P28347 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25876706 0.92 ADORA3 (0.36) KMT2AGAAHTTADORA3MEN1
SCHEMBL25876847 0.92 ADORA3 (0.36) ADORA3ABL1LCKFYNCSF1R
SCHEMBL25870131 0.90 ABL1 (0.38) KMT2AGAAHTTADORA3MEN1
SCHEMBL25875451 0.89 ABL1 (0.33) ADORA3ABL1LCKFYNCSF1R
SCHEMBL25876567 0.88 ABL1 (0.33) ADORA3ABL1LCKFYNCSF1R
SCHEMBL25876711 0.88 ABL1 (0.38) KMT2AGAAHTTADORA3MEN1
SCHEMBL25875671 0.88 KMT2A (0.43) KMT2AGAAHTTADORA3MEN1
SCHEMBL25874327 0.87 KDM4E (0.36) KMT2AGAATHRBHPGDKDM4E
SCHEMBL25875664 0.86 KMT2A (0.41) KMT2AGAAHTTADORA3MEN1
SCHEMBL25875786 0.86 KMT2A (0.37) KMT2AGAAHTTADORA3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134594-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134595-A1 POLYMERIZABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed