SCHEMBL25875488

SCHEMBL25875488

CC(F)(F)C(F)(F)Oc1ccc(Br)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 3/20 0.35
SCN1A P35498 1/20 0.35
KCNH2 Q12809 1/20 0.35
SCN5A Q14524 1/20 0.35
SCN9A Q15858 1/20 0.35
SCN2A Q99250 1/20 0.35
SCN8A Q9UQD0 1/20 0.35
SCN10A Q9Y5Y9 1/20 0.35
CYP2A6 P11509 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
LMNA P02545 1/20 0.34
MAPK1 P28482 1/20 0.34
RAB9A P51151 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30609397 0.83 PPARA (0.37) ALDH1A1KDM4EMAPTCYP2A6MEN1
SCHEMBL1230294 0.82 CYP2A6 (0.38) ALDH1A1KDM4EMAPTCYP2A6MEN1
SCHEMBL16546592 0.82 ALDH1A1 (0.40) ALDH1A1KDM4EMAPTSCN1AKCNH2
SCHEMBL4323037 0.82 CYP2A6 (0.38) ALDH1A1KDM4EMAPTCYP2A6MEN1
SCHEMBL20714605 0.80 CA1 (0.50) ALDH1A1KDM4EMAPTNPSR1MAPK1
SCHEMBL11716929 0.80 MAPT (0.37) ALDH1A1KDM4EMAPTCYP2A6MEN1
SCHEMBL23149109 0.78 ALDH1A1 (0.38) ALDH1A1KDM4EMAPTSCN1AKCNH2
SCHEMBL12012134 0.78 ALDH1A1 (0.45) ALDH1A1KDM4EMAPTMAPK1RAB9A
SCHEMBL13039942 0.77 CA4 (0.40) ALDH1A1KCNH2MAPK1PPARA
SCHEMBL21791780 0.77 CA1 (0.38) ALDH1A1KDM4EMAPTCYP2A6CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814463-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-20230227604-A1 FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2023-07-20 US disclosed
US-11643500-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-05-09 US disclosed