SCHEMBL25875492

SCHEMBL25875492

Cc1cccc(OC(F)(F)C(C)(F)F)c1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.50
LMNA P02545 2/20 0.43
AR P10275 1/20 0.42
ALDH1A1 P00352 2/20 0.42
L3MBTL1 Q9Y468 3/20 0.41
NPSR1 Q6W5P4 2/20 0.41
MAPK1 P28482 1/20 0.41
CHRM5 P08912 1/20 0.40
GAA P10253 2/20 0.40
SSTR1 P30872 1/20 0.38
SSTR4 P31391 1/20 0.38
HPGD P15428 1/20 0.37
GPR3 P46089 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
F2 P00734 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3904111 0.86 ACHE (0.52) ACHELMNAARALDH1A1L3MBTL1
SCHEMBL20752042 0.84 ACHE (0.54) ACHELMNAARALDH1A1L3MBTL1
SCHEMBL8460171 0.84 ACHE (0.54) ACHELMNAARALDH1A1L3MBTL1
SCHEMBL30072327 0.82 ACHE (0.56) ACHELMNAARALDH1A1L3MBTL1
SCHEMBL12245 0.82 ACHE (0.56) ACHELMNAARALDH1A1L3MBTL1
SCHEMBL16363563 0.81 ACHE (0.50) ACHELMNAARALDH1A1L3MBTL1
SCHEMBL10921751 0.80 ACHE (0.46) ACHELMNAARALDH1A1L3MBTL1
SCHEMBL5549887 0.80 ACHE (0.54) ACHELMNAARALDH1A1L3MBTL1
SCHEMBL5749658 0.79 ALDH1A1 (0.37) LMNAALDH1A1MAPK1GPR3TDP1
SCHEMBL7386225 0.79 ACHE (0.58) ACHELMNAARALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814463-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-20230227604-A1 FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2023-07-20 US disclosed
US-11643500-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-05-09 US disclosed