SCHEMBL25875521

SCHEMBL25875521

Cc1ccc(COC(F)(F)C(C)(F)F)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AGXT P21549 2/20 0.47
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
KCNH2 Q12809 1/20 0.37
IDO1 P14902 3/20 0.37
MAOB P27338 3/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
CYP1A2 P05177 1/20 0.34
CYP2A6 P11509 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
PARP10 Q53GL7 1/20 0.34
NAAA Q02083 1/20 0.34
AR P10275 1/20 0.34
CASP3 P42574 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16979036 0.81 AGXT (0.52) AGXTCA1CA2CA9KCNH2
SCHEMBL7935343 0.79 AGXT (0.54) AGXTCA1CA2CA9KCNH2
SCHEMBL19485039 0.75 KMT2A (0.35) CA1CA2CA9MAOB
SCHEMBL3424235 0.73 AGXT (0.48) AGXTCA1CA2CA9KCNH2
SCHEMBL16657032 0.72 AGXT (0.47) AGXTCA1CA2CA9KCNH2
SCHEMBL13698753 0.69 ALDH1A1 (0.58) AGXTCA1CA2CA9KCNH2
SCHEMBL10202767 0.69 TSHR (0.44) AGXTCA1CA2CA9IDO1
SCHEMBL18576980 0.69 AGXT (0.58) AGXTCA1CA2CA9KCNH2
SCHEMBL16378177 0.69 AGXT (0.58) AGXTCA1CA2CA9KCNH2
SCHEMBL8861635 0.68 BCHE (0.49) AGXTMAOBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814463-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-20230227604-A1 FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2023-07-20 US disclosed
US-11643500-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-05-09 US disclosed