Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM1A | O60341 | 5/20 | 0.50 |
| ▸ | MAOA | P21397 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | KDM1B | Q8NB78 | 4/20 | 0.50 |
| ▸ | RCOR1 | Q9UKL0 | 4/20 | 0.50 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.47 |
| ▸ | JAK3 | P52333 | 2/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.47 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21845725 | 0.90 | JAK2 (0.61) | KMT2AKDM1AMAOAMAOBKDM1B | |
| SCHEMBL25876036 | 0.78 | KMT2A (0.47) | RAB9ANPC1KMT2AKDM1AMAOA | |
| SCHEMBL25875892 | 0.78 | CYP1A2 (0.64) | MAOAMAOBHTR1A | |
| SCHEMBL22752055 | 0.77 | ROCK2 (0.67) | KDM1AMAOARCOR1JAK2ROCK2 | |
| SCHEMBL25875911 | 0.76 | CYP1A2 (0.56) | — | |
| SCHEMBL26455786 | 0.75 | ROCK2 (0.62) | JAK2ROCK2JAK3ROCK1HDAC1 | |
| SCHEMBL25875908 | 0.75 | NPC1 (0.69) | RAB9ANPC1KMT2ATNIK | |
| SCHEMBL12465050 | 0.74 | JAK2 (0.66) | JAK2ROCK2JAK3ROCK1HDAC1 | |
| SCHEMBL22752046 | 0.74 | JAK2 (0.66) | JAK2ROCK2JAK3ROCK1HDAC1 | |
| SCHEMBL25875889 | 0.74 | JAK2 (0.55) | RAB9ANPC1KMT2AKDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227430-A1 | ARYL CYCLOPROPYL-AMINO-ISOQUINOLINYL AMIDE COMPOUNDS | ALCON INC. (CH) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227430-A1 | ARYL CYCLOPROPYL-AMINO-ISOQUINOLINYL AMIDE COMPOUNDS | UACA, CHUK, MAP3K2 | RAB9A 992/4885NPC1 3861/4885KMT2A 2034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.