Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 17/20 | 0.70 |
| ▸ | RARB | P10826 | 5/20 | 0.70 |
| ▸ | RARG | P13631 | 5/20 | 0.70 |
| ▸ | RXRB | P28702 | 5/20 | 0.70 |
| ▸ | RXRG | P48443 | 5/20 | 0.70 |
| ▸ | RARA | P10276 | 4/20 | 0.70 |
| ▸ | HNF4A | P41235 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28321598 | 0.86 | RXRA (0.67) | RXRARARBRARGRXRBRXRG | |
| Hydrochloric Acid SCHEMBL28284311 | 0.85 | RXRA (0.66) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL7019809 | 0.84 | RXRA (0.56) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL30054740 | 0.82 | RXRA (1.00) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL726140 | 0.82 | RXRA (1.00) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL12181011 | 0.76 | RXRA (0.88) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL1073920 | 0.75 | RXRA (1.00) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL6906197 | 0.75 | RXRA (0.79) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL5540253 | 0.75 | RXRA (0.80) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL1072953 | 0.74 | RXRA (1.00) | RXRARARBRARGRXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141928-A1 | PROCESS FOR THE PREPARATION OF HIGHLY PURE BEXAROTENE | IND-SWIFT LABORATORIES LIMITED (IN) | 2011-11-17 | — | — | WO | disclosed |