Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 16/20 | 0.56 |
| ▸ | RARB | P10826 | 6/20 | 0.53 |
| ▸ | RARG | P13631 | 6/20 | 0.53 |
| ▸ | RXRB | P28702 | 6/20 | 0.53 |
| ▸ | RXRG | P48443 | 6/20 | 0.53 |
| ▸ | RARA | P10276 | 5/20 | 0.53 |
| ▸ | HNF4A | P41235 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890125 | 0.87 | RXRA (0.72) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL2587641 | 0.84 | RXRA (0.70) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL6890738 | 0.78 | RXRA (0.78) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL12426169 | 0.75 | RXRA (0.60) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL9118713 | 0.75 | P4HTM (0.56) | RXRARARBRARGRARAMEN1 | |
| SCHEMBL12425773 | 0.75 | RXRA (0.63) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL1073659 | 0.75 | RXRA (0.84) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL28321598 | 0.74 | RXRA (0.67) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL5537885 | 0.74 | RXRA (0.66) | RXRARARBRARGRXRBRXRG | |
| Hydrochloric Acid SCHEMBL28284311 | 0.73 | RXRA (0.66) | RXRARARBRARGRXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983991-B1 | Compounds having selectivity for retinoid x receptors | LIGAND PHARM INC (US) | 2003-12-17 | — | — | EP | disclosed |