SCHEMBL25876641

SCHEMBL25876641

C=C(C)C(=O)Oc1ccc(-c2ccc3c(oc4c(OC(F)(F)F)c(OC(=O)C(=C)C)ccc43)c2F)cc1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.36
ABL1 P00519 1/20 0.34
LCK P06239 1/20 0.34
FYN P06241 1/20 0.34
CSF1R P07333 1/20 0.34
LYN P07948 1/20 0.34
KIT P10721 1/20 0.34
SRC P12931 1/20 0.34
FLT1 P17948 1/20 0.34
FLT4 P35916 1/20 0.34
KDR P35968 1/20 0.34
FLT3 P36888 1/20 0.34
BLK P51451 1/20 0.34
ELANE P08246 1/20 0.34
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25876850 0.93 ADORA3 (0.38) ADORA3ABL1LCKFYNCSF1R
SCHEMBL25875452 0.92 ADORA3 (0.34) ADORA3ABL1LCKFYNCSF1R
SCHEMBL25876790 0.90 ABL1 (0.38) ADORA3ABL1LCKFYNCSF1R
SCHEMBL25876707 0.90 ADORA3 (0.36) ADORA3ABL1LCKFYNCSF1R
SCHEMBL25876794 0.89 ADORA3 (0.36) ADORA3ABL1LCKFYNCSF1R
SCHEMBL25875982 0.89 MAOA (0.38) ADORA3ELANEKMT2AATM
SCHEMBL25876288 0.88 ABL1 (0.38) ADORA3ABL1LCKFYNCSF1R
SCHEMBL25880426 0.86 MAOA (0.33)
SCHEMBL25875786 0.86 KMT2A (0.37) ADORA3ABL1LCKFYNCSF1R
SCHEMBL25876384 0.86 ELANE (0.35) ADORA3ELANEKMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134595-A1 POLYMERIZABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134594-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed