SCHEMBL25878006

SCHEMBL25878006

CC(C)(C)c1nc(-c2ccccc2)nc(-c2ccc(-c3ccc(-c4ccccc4)cc3)cc2)n1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.54
MEN1 O00255 6/20 0.46
KMT2A Q03164 6/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPT P10636 2/20 0.46
HPGD P15428 2/20 0.46
ADORA2A P29274 2/20 0.43
ADORA1 P30542 2/20 0.43
POLB P06746 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
ADORA2B P29275 1/20 0.43
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
NTSR1 P30989 1/20 0.41
IDH2 P48735 1/20 0.41
MAPK1 P28482 1/20 0.41
LMNA P02545 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19735249 1.00 L3MBTL1 (0.54) L3MBTL1MEN1KMT2AALDH1A1MAPT
SCHEMBL19862827 1.00 L3MBTL1 (0.54) L3MBTL1MEN1KMT2AALDH1A1MAPT
SCHEMBL25817457 0.96 L3MBTL1 (0.48) L3MBTL1MEN1KMT2AALDH1A1MAPT
SCHEMBL25817366 0.96 L3MBTL1 (0.48) L3MBTL1MEN1KMT2AALDH1A1MAPT
SCHEMBL15447621 0.96 L3MBTL1 (0.58) L3MBTL1MEN1KMT2AALDH1A1MAPT
SCHEMBL24622649 0.93 L3MBTL1 (0.47) L3MBTL1MEN1KMT2AALDH1A1MAPT
SCHEMBL25765455 0.93 L3MBTL1 (0.52) L3MBTL1MEN1KMT2AALDH1A1MAPT
SCHEMBL17878916 0.91 L3MBTL1 (0.52) L3MBTL1MEN1KMT2AALDH1A1MAPT
SCHEMBL22249621 0.91 L3MBTL1 (0.46) L3MBTL1MEN1KMT2AALDH1A1MAPT
SCHEMBL25762542 0.91 L3MBTL1 (0.46) L3MBTL1MEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM L3MBTL1 1994/4885MEN1 2884/4885KMT2A 3399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.