SCHEMBL25878113

SCHEMBL25878113

CC(C)(C)c1cccc(-c2ccccc2-c2ccccn2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.50
METAP2 P50579 1/20 0.45
TGFBR1 P36897 2/20 0.43
GRM5 P41594 6/20 0.42
TRPV1 Q8NER1 1/20 0.40
PTAFR P25105 1/20 0.40
KDM4E B2RXH2 2/20 0.39
LMNA P02545 2/20 0.39
CCR1 P32246 2/20 0.39
CCR5 P51681 2/20 0.39
CCR8 P51685 2/20 0.39
POLB P06746 2/20 0.39
CYP1A2 P05177 1/20 0.39
METAP1 P53582 1/20 0.39
BLM P54132 1/20 0.39
HIF1A Q16665 1/20 0.39
DOHH Q9BU89 1/20 0.39
P4HTM Q9NXG6 1/20 0.39
ABL1 P00519 1/20 0.39
BCR P11274 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30153625 0.87 KIF11 (0.56) KIF11METAP2TGFBR1GRM5TRPV1
SCHEMBL4404606 0.87 KIF11 (0.56) KIF11METAP2TGFBR1GRM5TRPV1
SCHEMBL25878105 0.84 KIF11 (0.57) KIF11METAP2TGFBR1TRPV1KDM4E
SCHEMBL11910216 0.83 KDM4E (0.52) TGFBR1GRM5KDM4ELMNACCR1
SCHEMBL16705325 0.82 KIF11 (0.49) KIF11METAP2TGFBR1GRM5TRPV1
SCHEMBL31039993 0.82 TRPV1 (0.52) KIF11METAP2TGFBR1TRPV1KDM4E
SCHEMBL31039977 0.79 GRM5 (0.56) TGFBR1GRM5KDM4ELMNACCR1
SCHEMBL27998333 0.78 GRM5 (0.50) TGFBR1GRM5KDM4ELMNACCR1
Hydrogen Sulfide SCHEMBL27798476 0.78 KIF11 (0.52) KIF11PTAFRL3MBTL1RXRARXRB
SCHEMBL20089430 0.78 KIF11 (0.46) KIF11PTAFRKDM4ELMNACCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM KIF11 3021/4885METAP2 2731/4885TGFBR1 2882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.