SCHEMBL25878226

SCHEMBL25878226

CC(C)(C)c1ncnc2c1ncn2-c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 8/20 0.60
PI4K2B Q8TCG2 8/20 0.60
PI4K2A Q9BTU6 8/20 0.60
PI4KB Q9UBF8 8/20 0.60
EGFR P00533 1/20 0.60
SLC2A1 P11166 1/20 0.47
SLC2A2 P11168 1/20 0.47
SLC2A3 P11169 1/20 0.47
XDH P47989 1/20 0.40
SRC P12931 2/20 0.39
FGFR1 P11362 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25886215 0.84 PI4KA (0.45) PI4KAPI4K2BPI4K2API4KBEGFR
SCHEMBL5146335 0.76 PI4KA (1.00) PI4KAPI4K2BPI4K2API4KBEGFR
SCHEMBL9150129 0.76 PI4KA (0.66) PI4KAPI4K2BPI4K2API4KBEGFR
SCHEMBL25878225 0.75 PI4KA (0.49) PI4KAPI4K2BPI4K2API4KBEGFR
SCHEMBL179252 0.73 ADORA1 (0.56) PI4KAPI4K2BPI4K2API4KB
SCHEMBL19207498 0.72 PI4KA (0.60) PI4KAPI4K2BPI4K2API4KBEGFR
SCHEMBL28950113 0.72 PI4KA (0.60) PI4KAPI4K2BPI4K2API4KBEGFR
SCHEMBL4569753 0.71 PI4KA (0.64) PI4KAPI4K2BPI4K2API4KBSRC
SCHEMBL31061395 0.71 EGFR (0.59) PI4KAPI4K2BPI4K2API4KBEGFR
SCHEMBL13170101 0.71 SLC2A1 (0.68) PI4KAPI4K2BPI4K2API4KBEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM PI4KA 3479/4885PI4K2B 4380/4885PI4K2A 4116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.