SCHEMBL25878391

SCHEMBL25878391

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc5c(c4)C4(c6cc(-c7ccc8oc9ccccc9c8c7)ccc6-5)C5CC6CC(C5)CC4C6)cc3)n2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.36
PLA2G4A P47712 3/20 0.36
HTT P42858 1/20 0.33
CHEK2 O96017 1/20 0.33
PIM1 P11309 2/20 0.32
PIM3 Q86V86 2/20 0.32
PIM2 Q9P1W9 2/20 0.32
TBK1 Q9UHD2 1/20 0.32
ALDH1A1 P00352 6/20 0.32
MAPT P10636 4/20 0.32
HPGD P15428 4/20 0.32
KDM4E B2RXH2 3/20 0.32
TSHR P16473 2/20 0.32
ALOX15 P16050 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PLA2G10 O15496 1/20 0.32
LMNA P02545 2/20 0.32
KMT2A Q03164 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25879221 0.99 PLA2G2A (0.34) PLA2G2APLA2G4AHTTCHEK2PIM1
SCHEMBL23606115 0.97 PLA2G2A (0.34) PLA2G2APLA2G4AHTTCHEK2PIM1
SCHEMBL25038163 0.95 PLA2G2A (0.33) PLA2G2APLA2G4AHTTCHEK2PIM1
SCHEMBL23605940 0.95 HTT (0.33) PLA2G2APLA2G4AHTTCHEK2PIM1
SCHEMBL24608719 0.94 PLA2G2A (0.32) PLA2G2APLA2G4AHTTCHEK2PIM1
SCHEMBL23609539 0.94 HTT (0.33) PLA2G2APLA2G4AHTTPIM1PIM3
SCHEMBL24608808 0.93 PLA2G2A (0.32) PLA2G2APLA2G4AALDH1A1MAPTHPGD
SCHEMBL24608695 0.93 PLA2G2A (0.32) PLA2G2APLA2G4AHTTCHEK2PIM1
SCHEMBL25035862 0.93 MAPT (0.33) HTTCHEK2PIM1PIM3PIM2
SCHEMBL25878376 0.93 HTT (0.34) HTTALDH1A1MAPTHPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM PLA2G2A 4098/4885PLA2G4A 4485/4885HTT 3418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.