Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.74 |
| ▸ | RAB9A | P51151 | 5/20 | 0.74 |
| ▸ | LMNA | P02545 | 4/20 | 0.74 |
| ▸ | POLB | P06746 | 4/20 | 0.74 |
| ▸ | GFER | P55789 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | HPGD | P15428 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25878920 | 0.85 | KDM4E (0.67) | KDM4ESMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL4727616 | 0.83 | KDM4E (0.82) | KDM4ESMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL29466392 | 0.83 | KDM4E (0.71) | KDM4ESMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL25312971 | 0.83 | KDM4E (0.71) | KDM4ESMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL3661290 | 0.82 | CLK1 (0.67) | KDM4ESMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL25876071 | 0.82 | KDM4E (0.73) | KDM4ESMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL25263897 | 0.81 | KDM4E (0.65) | KDM4ESMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL4781504 | 0.81 | KDM4E (0.77) | KDM4ESMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL28933829 | 0.80 | ALDH1A1 (0.78) | KDM4ESMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL4726403 | 0.80 | KDM4E (0.76) | KDM4ESMN1; SMN2RAB9ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |