SCHEMBL25878936

SCHEMBL25878936

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)C3(c5cc(-c6ccc7c(c6)C(c6ccccc6)(c6ccccc6)c6ccccc6-7)ccc5-4)C4CC5CC(C4)CC3C5)n2)cc1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
MAPT P10636 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
OPRK1 P41145 1/20 0.34
PDK2 Q15119 5/20 0.34
HSD11B1 P28845 2/20 0.33
HTT P42858 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
NTSR1 P30989 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24608708 0.95 PDK2 (0.32) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL24608843 0.91 PDK2 (0.32) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL24608782 0.91 MEN1 (0.33) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL25878939 0.90 MEN1 (0.36) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL23605935 0.90 MEN1 (0.38) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL23606089 0.89 MEN1 (0.35) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL23605825 0.89 HTT (0.32) HTT
SCHEMBL25035934 0.89 PDK2 (0.36) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL24618024 0.88 MEN1 (0.39) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL24617955 0.88 MEN1 (0.41) MEN1KMT2AMAPTSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM MEN1 2884/4885KMT2A 3399/4885MAPT 1215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.