SCHEMBL25878939

SCHEMBL25878939

c1ccc(-c2cc(-c3ccc4c(c3)C3(c5ccc(-c6ccc7c(c6)C(c6ccccc6)(c6ccccc6)c6ccccc6-7)cc5-4)C4CC5CC(C4)CC3C5)nc(-c3ccccc3)n2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
HPGD P15428 4/20 0.36
MAPT P10636 4/20 0.36
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 3/20 0.36
LMNA P02545 3/20 0.36
GLA P06280 1/20 0.36
NTSR1 P30989 1/20 0.34
MAOB P27338 2/20 0.31
MAOA P21397 1/20 0.31
PDK2 Q15119 2/20 0.31
ADORA3 P0DMS8 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31
OPRK1 P41145 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24608843 0.91 PDK2 (0.32) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL24608782 0.91 MEN1 (0.33) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL25878936 0.90 MEN1 (0.34) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL24608708 0.89 PDK2 (0.32) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL23606089 0.88 MEN1 (0.35) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL24608805 0.86 PDK2 (0.32) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL24608880 0.86 PDK2 (0.34) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL24608898 0.86 MEN1 (0.34) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL25582386 0.85 PDK2 (0.34) MEN1KMT2AALDH1A1LMNAPDK2
SCHEMBL24618074 0.84 MEN1 (0.39) MEN1KMT2AHPGDMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM MEN1 2884/4885KMT2A 3399/4885HPGD 2843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.