Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25311112 | 0.87 | KDM4E (0.55) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL25311377 | 0.85 | KDM4E (0.62) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL19322175 | 0.83 | KDM4E (0.60) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL25878977 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL29484624 | 0.81 | RAB9A (0.56) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL25311588 | 0.81 | RAB9A (0.56) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL25311960 | 0.81 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL25312109 | 0.80 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL30471101 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL25310936 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114195780-A | Carbonyl heterocyclic compound and application thereof | 上海医药集团股份有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114195806-A | Carbonyl heterocyclic compound and application thereof | 上海医药集团股份有限公司 | 2022-03-18 | — | — | CN | disclosed |