SCHEMBL25879053

SCHEMBL25879053

Clc1ccc2c(c1)-c1ccc(-c3ccc4ccccc4c3)cc1C21C2CC3CC(C2)CC1C3

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.37
CNR1 P21554 1/20 0.34
PDK2 Q15119 4/20 0.34
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
HTT P42858 2/20 0.32
ABL1 P00519 3/20 0.32
KDR P35968 1/20 0.32
GSTP1 P09211 1/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
SLC6A4 P31645 1/20 0.31
PGR P06401 2/20 0.31
LMNA P02545 2/20 0.31
MAPT P10636 2/20 0.31
RARA P10276 2/20 0.31
RARB P10826 2/20 0.31
RARG P13631 2/20 0.31
NR1I2 O75469 1/20 0.31
HSPD1 P10809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25879051 0.89 PDK2 (0.39) PDK2MEN1KMT2APGRLMNA
SCHEMBL25962064 0.89 PDK2 (0.39) PDK2MEN1KMT2APGRLMNA
SCHEMBL25038158 0.86 PDK2 (0.39) CYP2A6PDK2HTTSLC6A4LMNA
SCHEMBL25501628 0.84 CYP2A6 (0.31) CYP2A6
SCHEMBL25879028 0.84 PDK2 (0.38) PDK2PGR
SCHEMBL24316940 0.83 PDK2 (0.39) CYP2A6PDK2HTTSLC6A4LMNA
SCHEMBL25501424 0.83 PDK2 (0.38) PDK2ALDH1A1CYP3A4HPGD
SCHEMBL25501542 0.83 PDK2 (0.33) PDK2PGR
SCHEMBL25879052 0.83 MEN1 (0.35) PDK2MEN1KMT2AHTTPGR
SCHEMBL30593260 0.82 PDK2 (0.41) PDK2PGRNR1I2ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM CYP2A6 3334/4885CNR1 4566/4885PDK2 639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.