Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.69 |
| ▸ | HPGD | P15428 | 5/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | GFER | P55789 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SMO | Q99835 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29484589 | 0.88 | ALDH1A1 (0.66) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL29484580 | 0.82 | ALDH1A1 (0.81) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL25312016 | 0.82 | ALDH1A1 (0.81) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL28933829 | 0.80 | ALDH1A1 (0.78) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL1494696 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL25311124 | 0.78 | LANCL2 (0.59) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL29466265 | 0.78 | LANCL2 (0.59) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL14076569 | 0.77 | KDM4E (0.72) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL25311377 | 0.76 | KDM4E (0.62) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL4729920 | 0.76 | ALDH1A1 (1.00) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |