Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 1.00 |
| ▸ | LMNA | P02545 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.80 |
| ▸ | HPGD | P15428 | 4/20 | 0.80 |
| ▸ | RAB9A | P51151 | 4/20 | 0.80 |
| ▸ | TP53 | P04637 | 3/20 | 0.80 |
| ▸ | NPC1 | O15118 | 2/20 | 0.80 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | GFER | P55789 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1494696 | 0.89 | KDM4E (1.00) | ALDH1A1LMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL13401433 | 0.87 | ALDH1A1 (0.77) | ALDH1A1LMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL25312016 | 0.83 | ALDH1A1 (0.81) | ALDH1A1LMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL29484580 | 0.83 | ALDH1A1 (0.81) | ALDH1A1LMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL28933829 | 0.81 | ALDH1A1 (0.78) | ALDH1A1LMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL14076569 | 0.78 | KDM4E (0.72) | ALDH1A1LMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL1494939 | 0.76 | ALDH1A1 (0.77) | ALDH1A1LMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL1494791 | 0.76 | GFER (0.79) | ALDH1A1LMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL25879189 | 0.76 | KDM4E (0.69) | ALDH1A1LMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL25876071 | 0.75 | KDM4E (0.73) | ALDH1A1LMNAMAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029152-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2008-03-13 | — | — | WO | disclosed |