Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 11/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25879275 | 0.91 | CFD (0.47) | CFDFFAR1 | |
| SCHEMBL25879178 | 0.91 | CFD (0.47) | CFDMEN1KMT2AFFAR1 | |
| SCHEMBL21438708 | 0.90 | CFD (0.44) | CFDPDE10APDE3BPDE3AMEN1 | |
| SCHEMBL25879271 | 0.89 | CFD (0.45) | CFDFFAR1 | |
| SCHEMBL25878866 | 0.89 | CFD (0.54) | CFD | |
| SCHEMBL21438302 | 0.88 | CFD (0.53) | CFDPDE10APDE3BPDE3AFFAR1 | |
| SCHEMBL21437898 | 0.86 | CFD (0.42) | CFDPDE10APDE3BPDE3AMEN1 | |
| SCHEMBL25879282 | 0.85 | CFD (0.47) | CFDMEN1KMT2AFFAR1THRA | |
| SCHEMBL21438448 | 0.85 | CFD (0.59) | CFDPDE10APDE3BPDE3AHSD17B10 | |
| SCHEMBL21438430 | 0.84 | CFD (0.40) | CFDPDE10APDE3BPDE3AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708347-B2 | Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708347-B2 | Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors | C9, C5, C1QBP | CFD 17/4885PDE10A 4039/4885PDE3B 1963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.